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Author Topic: A Fresh Look at Chemotherapy  (Read 217 times)

Offline danialthomas

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A Fresh Look at Chemotherapy
« on: December 10, 2021, 05:33:38 pm »
My job as a physician is to do what it takes to help my cancer patient achieve remission. For those who fear chemotherapy because of its side effects or have become discouraged by chemotherapy because it eventually stopped working, the protocol below should be considered. Due to the low dose of chemotherapy drugs used, treatment is generally well tolerated with most patients experiencing no severe side effects.

Once-a-week, in-office treatment:
• Intravenous artesunate immediately followed by…
• Intravenous high-dose vitamin C plus doxycycline and azithromycin immediately followed by…
• Intravenous chemotherapy combining 3-5 synergistic drugs used for the cancer type at 1/3 to 1/5 the normal dose. This is combined with intravenous curcumin to decrease chemoresistance and reduce chemotherapy side effects, along with hyperthermia to improve drug delivery, disable the intracellular DNA repair enzymes that allow cancer to survive chemotherapy, and induce cancer cells to release heat-shock proteins and tumor-specific antigens that attract cancer-killing tumor-infiltrating lymphocytes and Natural Killer cells.

Supporting oral protocol:
• Ivermectin and pentoxifylline to promote chemosensitivity and inhibit chemoresistance
• Piperlongumine to impair cancer’s thioredoxin and glutathione antioxidant defense mechanisms
• Luteolin to promote cell cycle arrest and apoptosis
• Metformin and syrosingopine to impair cancer bioenergetics
• Low-dose naltexone to enhance the immune response against cancer
• Pro-resolving mediators to promote the removal of tumor debris

Dr. Daniel Thomas, DO, MS
Mount Dora, Florida

References:

Benjamin D, Robay D, Hindupur SK, Pohlmann J, Colombi M, El-Shemerly MY, Maira SM, Moroni C, Lane HA, Hall MN. Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells. Cell Rep. 2018 Dec 11;25(11):3047-3058.e4.
Fiorillo M, Tóth F, Sotgia F, Lisanti MP. Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs). Aging (Albany NY). 2019 Apr 19;11(8):2202-2216.
Golunski G, Woziwodzka A, Piosik J. Potential Use of Pentoxifylline in Cancer Therapy. Curr Pharm Biotechnol. 2018;19(3):206-216.
Hannon, G., Tansi, F.L., Hilger, I. and Prina-Mello, A. (2021), The Effects of Localized Heat on the Hallmarks of Cancer. Adv. Therap., 4: 2000267.
Imran M, Rauf A, Abu-Izneid T, Nadeem M, Shariati MA, Khan IA, Imran A, Orhan IE, Rizwan M, Atif M, Gondal TA, Mubarak MS. Luteolin, a flavonoid, as an anticancer agent: A review. Biomed Pharmacotherapy. 2019 Apr;112:108612.
Juarez M, Schcolnik-Cabrera A, Dueñas-Gonzalez A. The multitargeted drug ivermectin: from an antiparasitic agent to a repositioned cancer drug. Am J Cancer Res. 2018;8(2):317-331.
Li Z, You Y, Griffin N, Feng J, Shan F. Low-dose naltrexone (LDN): A promising treatment in immune-related diseases and cancer therapy. Int Immunopharmacol. 2018 Aug;61:178-184.
Liu Z, Huang P, Law S, Tian H, Leung W, Xu C. Preventive Effect of Curcumin Against Chemotherapy-Induced Side-Effects. Front Pharmacol. 2018 Nov 27;9:1374.
Ong CP. High Dose Vitamin C and Low Dose Chemo Treatment. J Cancer Sci. 2018;5(1): 4.
Shaikh S, Shaikh J, Naba YS, Doke K, Ahmed K, Yusufi M. Curcumin: reclaiming the lost ground against cancer resistance. Cancer Drug Resist 2021;4:298-320.
Slezakova S, Ruda-Kucerova J. Anticancer Activity of Artemisinin and its Derivatives. Anticancer Res. 2017 Nov;37(11):5995-6003.
Wang H, Jiang H, Corbet C, de Mey S, Law K, Gevaert T, Feron O, De Ridder M. Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems. Cancer Lett. 2019 May 28;450:42-52.
Zhang Q, Zhu B, Li Y. Resolution of Cancer-Promoting Inflammation: A New Approach for Anticancer Therapy. Front Immunol. 2017 Feb 2;8:71.

Disclaimer:

This information is for educational purposes only and not intended or implied to be a substitute for professional medical advice, diagnosis, treatment, and monitoring by your personal physician. Therefore, I cannot answer questions regarding appropriateness in your situation nor give treatment advice. That is for your personal physician to determine after he or she carefully studies the references above.
Located in Mount Dora, Florida, Dr. Thomas is one of the most educated, experienced, and innovative physicians in North America. Over the past 30 years, he has helped people throughout the United States and Canada to prevent and overcome disease, improve their health, slow aging, and increase their lifespan. As an active translational researcher, Dr. Thomas has spent over 35,000 hours poring over the latest scientific discoveries and translating max. discoveries into promising theories

 


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