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Author Topic: New Cancer Drug Mimics Virus and Outmaneuvers Tumor Cells  (Read 953 times)

Offline iana5252

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New Cancer Drug Mimics Virus and Outmaneuvers Tumor Cells
« on: November 04, 2020, 11:30:32 am »
A novel cancer drug that mimics a virus helps the immune system identify and target tumors that might otherwise be missed by immunotherapy. These findings were published in Science Translational Medicine. 

“In some patients, tumors escape the immune system through mutations in genes involved in the interferon signaling pathway,” coauthor Anusha Kalbasi, MD, of the University of California, Los Angeles (UCLA), said in a press release. “This is a critical pathway because it normally allows tumors to increase their antigen presentation, an intricate machinery that makes tumors visible to T cells.”

Called BO-112, the new drug resembles the double-stranded RNA structure found in certain viruses that can stimulate an immune response. Once inside a tumor, BO-112 has the ability to alert the immune system and kick-start a protective response to attack cancer cells. 

Read more:
https://www.cancerhealth.com/article/new-cancer-drug-mimics-virus-outmaneuvers-tumor-cells

 


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