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Author Topic: Cancer Stem Cells  (Read 243 times)

Offline danialthomas

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Cancer Stem Cells
« on: January 17, 2020, 03:20:10 pm »
In the human body, there are healthy stem cells that help repair and regenerate damaged tissues. Similarly, in tumors, there are cancer stem cells (CSCs) that help repair and regenerate tumors. This subset of cancer cells is also known as tumor-survival cells (TSCs) or tumor-initiating cells (TICs). Many experts believe that successful eradication of CSCs could change the face of cancer treatment. Not only are CSCs the main driver of distant metastasis, treatment failure, and disease recurrence, CSCs may also be the root cause of the original tumor itself. Because of the powerful survival mechanisms of CSCs, chemotherapy, radiation, and surgery are unable to kill them. In fact, conventional therapy can do the exact opposite and stimulate the proliferation and virulence of CSCs.

CSCs can migrate and nest in various areas of the body and remain dormant for months, years, or even decades until the right stimulus comes along and awakens them. While conventional therapy can eradicate the bulk (main) tumor cells, sooner or later, lingering CSCs can form new and often more aggressive tumors from a small number of cells (as few as 100). In other words, being “tumor-free” is not the same as being “cancer-free.” Eradicating the bulk tumor cells is not enough. CSCs must also be eradicated to achieve long-term survival. At present, there are no drugs that are FDA-approved to specifically target CSCs. To address this urgent and unmet need, we are pioneering the use of repurposed medicines and natural compounds that have been shown to target CSCs by killing them and/or preventing them from entering a dormant and more resistant state.

Dr. Daniel Thomas, DO, MS
Mount Dora, Florida

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« Last Edit: January 23, 2020, 11:02:35 am by Cancer Health Forum Moderators »
Located in Mount Dora, Florida, Dr. Thomas is one of the most educated, experienced, and innovative physicians in North America. Over the past 30 years, he has helped people throughout the United States and Canada to prevent and overcome disease, improve their health, slow aging, and increase their lifespan. As an active translational researcher, Dr. Thomas has spent over 35,000 hours poring over the latest scientific discoveries and translating max. discoveries into promising theories

 


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